alexa Second Generation DES: Better Option in Treatment ISR
ISSN: 2329-6925

Journal of Vascular Medicine & Surgery
Open Access

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Research Article

Second Generation DES: Better Option in Treatment ISR

Hristova N*, Trendafilova D and Jorgova J

University Hospital “St Ekaterina”, Clinic of Cardiology and Cardiosurgery, 52 A Bul. Pencho Slavejkov, 1431 Sofia, Bulgaria

*Corresponding Author:
Nadezhda Hristova
Cardiology clinic, University hospital “St. Ekaterina”
bul. Pencho Slaveikov 52 A, Sofia, Bulgaria
+359 895418911; +35929549057
E-mail: [email protected]

Received Date: March 17, 2014; Accepted Date: April 28, 2014; Published Date: April 30, 2014

Citation: Hristova N, Trendafilova D, Jorgova J (2014) Second Generation DES: Better Option in Treatment ISR. J Vasc Med Surg 2:133. doi: 10.4172/2329-6925.1000133

Copyright: © 2014 Hristova N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The development of an effective strategy for treatment of in-stent restenosis after BMS placement has been found to be extremely complicated. The therapeutic purpose for many patients is achieved with the implantation of DES – an option which is still not investigated and studied enough. 152 patients with implanted drug-eluting stents (different generations) for severe in-stent restenosis were followed up for a period of 9 years in the department of cardiology of University Hospital “St. Ekaterina”. Patients were divided into two groups – 131 patients with implanted first generation DES, and 21 patients – with second generation DES. Patients were followed up clinically (reversed angina, MI, emergency CABG, death), EchoCG and/or ECG stress test. Patients with angina pectoris and/or decreased LV function were assessed by conventional or CT angiography. Serious complications were not observed. 9 patients were with significant in-stent proliferation, and the others were with patent stents. Implementation of DES for treatment of in-stent restenosis is an established method, because of its reliability and safety with low percentage of complications.


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