Secondary Metabolites of Lichens as Both Anti-aggregative and Antioxidant Agents in TauopathiesAlberto Cornejo1* and Carlos Areche2
- *Corresponding Author:
- Alberto Cornejo
Faculty of Medicine, School of Medical Technology, Andrés Bello University
Sazié 2315, First Floor, Santiago 8370092, Chile
E-mail: [email protected]
Received date: February 01, 2017; Accepted date: March 30, 2017; Published date: April 11, 2017
Citation: Cornejo A, Areche C (2017) Secondary Metabolites of Lichens as Both Anti-aggregative and Antioxidant Agents in Tauopathies. J Clin Cell Immunol 8:496. doi: 10.4172/2155-9899.1000496
Copyright: © 2017 Cornejo A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This commentary described our findings of parietin, an anthraquinone, isolated from Ramalina terebrata as inhibitor of tau protein. Moreover, we considered important to link tauopathies with reactive oxygen species since oligomers and fibril-forming elements are responsible for activating reactive oxygen species, which cause inflammatory response and neurodegeneration. Together, we considered important to find naturally occurring compounds that might be able to stop aggregation and reduces ROS cells damage.