alexa Self-retained Amniotic Membrane Transplantation for Recurrent Corneal Erosion
ISSN: 2155-9570

Journal of Clinical & Experimental Ophthalmology
Open Access

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Research Article

Self-retained Amniotic Membrane Transplantation for Recurrent Corneal Erosion

Yukan Huang1,2, Hosam Sheha1 and Scheffer CG Tseng1*
1Ocular Surface Center, Miami, FL, USA, Ocular Surface Research Education Foundation, and TissueTech, Inc., Miami, FL, USA
2Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Corresponding Author : Scheffer CG Tseng, MD, PhD
Ocular Surface Center, 7000 SW 97 Avenue
Suite 213. Miami, FL 33173, USA
Tel: (305)274-1299
Fax: (305)274-1297
E-mail: [email protected]
Received: February 27, 2013; Accepted: March 22, 2013; Published: March 29, 2013
Citation:Huang Y, Sheha H, Tseng SCG (2013) Self-retained Amniotic Membrane Transplantation for Recurrent Corneal Erosion. J Clin Exp Ophthalmol 4:272. doi:10.4172/2155-9570.1000272
Copyright: © 2013 Huang Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Purpose: To evaluate the efficacy of placement of sutureless self-retained cryopreserved amniotic membrane in treating recurrent corneal erosion (RCE).

Methods: Eleven eyes of 9 consecutive patients with RCE received epithelial debridement and placement of ProKera® (Bio-Tissue, Inc, Miami, Florida, USA). Their clinical outcomes were retrospectively reviewed.

Results: Although corneal signs suggestive of RCE were found in 7 of 11 eyes, diagnosis of the remaining 4 eyes, including two eyes with predominant lid discomfort, was not made until the use of the cellulose sponge test to elicit a wrinkled epithelium. After debridement and placement of ProKera®, complete epithelialization was noted in all eyes in 4 to 7 days. During the follow up of 13.7 ± 2.2 months, one eye recurred and required repeated treatment. Afterwards, all eyes were asymptomatic and regained a smooth and stable corneal epithelium. Best-corrected visual acuity was improved to at least 20/30 in all 6 eyes complaining of blurry vision and involving the visual axis.

Conclusions: Debridement followed by placement of self-retained cryopreserved amniotic membrane via ProKera® can be performed in the office for treating RCE. Further studies to validate its efficacy in comparison to other surgeries are warranted.

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