Self-retained Amniotic Membrane Transplantation for Recurrent Corneal Erosion
|Yukan Huang1,2, Hosam Sheha1 and Scheffer CG Tseng1*|
|1Ocular Surface Center, Miami, FL, USA, Ocular Surface Research Education Foundation, and TissueTech, Inc., Miami, FL, USA|
|2Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China|
|Corresponding Author :||Scheffer CG Tseng, MD, PhD
Ocular Surface Center, 7000 SW 97 Avenue
Suite 213. Miami, FL 33173, USA
E-mail: [email protected]
|Received: February 27, 2013; Accepted: March 22, 2013; Published: March 29, 2013|
|Citation:Huang Y, Sheha H, Tseng SCG (2013) Self-retained Amniotic Membrane Transplantation for Recurrent Corneal Erosion. J Clin Exp Ophthalmol 4:272. doi:10.4172/2155-9570.1000272|
|Copyright: © 2013 Huang Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
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Purpose: To evaluate the efficacy of placement of sutureless self-retained cryopreserved amniotic membrane in treating recurrent corneal erosion (RCE).
Methods: Eleven eyes of 9 consecutive patients with RCE received epithelial debridement and placement of ProKera® (Bio-Tissue, Inc, Miami, Florida, USA). Their clinical outcomes were retrospectively reviewed.
Results: Although corneal signs suggestive of RCE were found in 7 of 11 eyes, diagnosis of the remaining 4 eyes, including two eyes with predominant lid discomfort, was not made until the use of the cellulose sponge test to elicit a wrinkled epithelium. After debridement and placement of ProKera®, complete epithelialization was noted in all eyes in 4 to 7 days. During the follow up of 13.7 ± 2.2 months, one eye recurred and required repeated treatment. Afterwards, all eyes were asymptomatic and regained a smooth and stable corneal epithelium. Best-corrected visual acuity was improved to at least 20/30 in all 6 eyes complaining of blurry vision and involving the visual axis.
Conclusions: Debridement followed by placement of self-retained cryopreserved amniotic membrane via ProKera® can be performed in the office for treating RCE. Further studies to validate its efficacy in comparison to other surgeries are warranted.