Separation/Analysis of Chrysophanol by Ionic Liquid Loaded ÃÂ²-Cyclodextrin Polymer Coupled with Ultraviolet Spectrophotometry
Wenhui Ping, Hongyan Xu and Xiashi Zhu*
College of Chemistry and Chemical Engineering, Yangzhou University, China
- *Corresponding Author:
- Xiashi Zhu
College of Chemistry and
Yangzhou University, China
E-mail: [email protected]
Received Date: August 21, 2013; Accepted Date: September 16, 2013; Published Date: September 19, 2013
Citation: Ping W, Xu H, Zhu X (2013) Separation/Analysis of Chrysophanol by Ionic Liquid Loaded β-Cyclodextrin Polymer Coupled with Ultraviolet Spectrophotometry. Biochem Anal Biochem 2:138. doi: 10.4172/2161-1009.1000138
Copyright: © 2013 Ping W. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A novel method for separation/analysis of chrysophanol (Chry) in drugs is described. The work is based on the utilization of ionic liquid ([C4min] PF6) (IL) loaded β-cyclodextrin cross-linked polymer (IL-β-CDCP) for effective adsorption of Chry coupled with ultraviolet spectrophotometry for the analysis of Chry. The inclusion interaction of IL-β-CDCP with Chry is studied by FTIR and 13C-NMR. Under the optimum conditions, linear range, Detection Limit (DL) and the relative standard deviation are 0.10-20.0 μg mL-1, 0.02 μg mL-1, 0.45% (n=3, c=4.0 μg mL-1), respectively. This technique is successfully applied for determination of Chry in drug samples.