Journal of Medical Diagnostic Methods
Open Access

Abstract

Sequential Serum Phosphate and Urinary Biochemical Changes in Postoperative Systemic Inflammatory Response Syndrome: Potential Additional Diagnostic Tools in Acute Kidney Injury

Alexandre Toledo Maciel and Daniel Vitorio

Systemic inflammatory response syndrome (SIRS) is frequent after major surgery and may lead to multiple organ failure. Many classical parameters such as leukocytes and platelets count, lactate and c-reactive protein are measured sequentially during SIRS in order to quantify the severity of the inflammatory/metabolic stress. Blood urea nitrogen and creatinine are usually assessed to evaluate renal function since acute kidney injury (AKI) is a frequent complication of SIRS. The aim of this case report is to describe sequential serum phosphate and sodium and potassium measurement in urine in parallel with AKI development and recovery. The aim is to suggest that these parameters may help in AKI monitoring in the context of SIRS.