alexa Serous Endometrial Intraepithelial Carcinoma Involving
ISSN: 2165-7920

Journal of Clinical Case Reports
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Research Article

Serous Endometrial Intraepithelial Carcinoma Involving Endometrial Polyp Diagnosed by Transcervical Resection: A Case Report

Takayuki Ichinose1, Shunsuke Nakagawa1*, Shigenari Namai1, Masahiro Shiba1, Minako Shimizu1, Ranka Kanda1, Takeru Sugihara1,Masayoshi Morita1, Yuko Sasajima2, Fukuo Kondo2, Hiroshi Uozaki2 and Takuya Ayabe1
1Department of Obstetrics and Gynecology, Graduate School of Medicine, Teikyo University, Tokyo, Japan
2Department of Pathology, Graduate School of Medicine, Teikyo University, Tokyo, Japan
Corresponding Author : Shunsuke Nakagawa
Department of Obstetrics and Gynecology
Graduate School of Medicine
Teikyo University
Tokyo, Japan
Tel: 81-3- 3964-1211
Fax: 81-3-5373-1274
E-mail: [email protected]
Received December 13, 2015; Accepted January 05, 2016; Published January 12, 2016
Citation: Ichinose T, Nakagawa S, Namai S, Shiba M, Shimizu M, et al. (2016) Serous Endometrial Intraepithelial Carcinoma Involving Endometrial Polyp Diagnosed by Transcervical Resection: A Case Report. J Clin Case Rep 6:678. doi:10.4172/2165-7920.1000678
Copyright: © 2016 Ichinose T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Related article at Pubmed, Scholar Google


Uterine serous carcinoma is a representative histological subtype of endometrial type II cancer. Uterine
serous intraepithelial carcinoma
is thought to be a precursor lesion of uterine serous carcinoma. Uterine serous
intraepithelial carcinoma is frequently found to involve an endometrial polyp. Preoperative diagnosis of uterine serous
intraepithelial carcinoma is difficult due to its localized occurrence in the endometrial cavity. We experienced a case
of postmenopausal women with abnormal endometrial cytology. Endometrial biopsy suggested the possibility that
she has a malignant uterine tumor, but it did not reached to the confirmative pathological diagnosis. Hysteroscopy
revealed that she has an endometrial polyp. Pathological analysis of the resected endometrial polyp confirmed that
her disease is uterine serous intraepithelial carcinoma involving endometrial polyp. She underwent hysterectomy,
bilateral salpingo-oophorectomy, omentectomy and retroperitoneal lymphadenectomy. No extrauterine lesion was
detected. Our case suggested the possibility that transcervical resection under the hysteroscope might be useful to
detect serous endometrial intraepithelial carcinoma.


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