alexa Sertoli–Leydig Tumor and Meigs’ Syndrome, an Infrequent Association-A Case Report
[Jurnalul de Chirurgie]
ISSN: 1584-9341

Journal of Surgery
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Case Report

Sertoli–Leydig Tumor and Meigs’ Syndrome, an Infrequent Association-A Case Report

Jessica Salazar Campos1, Víctor Hugo Moreno Salazar1, Alhely López Arias1, María Delia Pérez Montiel Gómez2 and David Cantú de León1*

1Department of Gynecology Oncology, Instituto Nacional de Cancerología de México, México

2Department of Pathology, Instituto Nacional de Cancerología de México, México

*Corresponding Author:
David Cantú de León
Gynecology Oncology Department
Subdirección de Investigación Clínica
Instituto Nacional de Cancerología de México
Av. San Fernando #22 Col. Sección XVI
Tlalpan, C.P. 14080, México
Tel: +525-556- 280-400
Fax: +525-556-280-425
E-mail: [email protected]

Received Date: February 18, 2016; Accepted Date: May 04, 2016; Published Date: May 11, 2016

Citation: Campos JS, Salazar VHM, Arias AL, Gómez MDPM, León DCD. Sertoli–Leydig Tumor and Meigs’ Syndrome, an Infrequent Association-A Case Report. Journal of Surgery [Jurnalul de chirurgie]. 2016; 12(2): 65-69 DOI: 10.7438/1584-9341-12-2-5

Copyright: © 2016 Campos JS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The Meigs’ syndrome, of infrequent presentation in approximately 4% of benign ovarian tumors, is characterized by the association of a benign tumor of gynecological origin with ascites and pleural effusion, which, in the majority of cases, induces the Clinician to suspect a malignant etiology. However, these conditions are resolved after tumor excision. Fewer than 60 cases of Meigs’ syndrome have been reported in the literature to date that have a rise in the CA 125 antigen. The first case was documented by Jones and Survit in 1989 in a 70-year-old patient with a fibrothecoma and with an elevation of CA 125 of 226 IU/ml. The association of a Meigs’ syndrome with Sertoli–Leydig tumors is extremely rare, we present the second case reported in the literature. The fact of being able to find the association of these two entities renders it evident that the Clinician should bear this in mind at the time of carrying out the evaluation of a patient with a pelvic injury that is bears a resemblance to advanced-stage ovarian cancer, and even more so if it presents with elevations of CA 125, in that Meigs syndrome will present complete resolution after the tumor excision.


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