alexa Serum Vitamin D Level in Children with and without Type 1 Diabetes Mellitus
ISSN: 2155-6156

Journal of Diabetes & Metabolism
Open Access

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Research Article

Serum Vitamin D Level in Children with and without Type 1 Diabetes Mellitus

Halioui-Louhaichi Sonia1*, Mrabet Ali2, Dridi Yousr1, Barbaria Wiem1, Hamzaoui Anies3 Hamzaoui Kamel3 and Maherzi Ahmed1

1Pediatric Department of Mongi Slim Hospital La Marsa, Medicine Faculty of Tunis, University of Tunis El Manar, Tunisia

2Military Center of Hygiene and Protection of the Environment, Medicine Faculty of Tunis, University of Tunis El Manar, Tunisia

3University of Tunis El Manar, Medicine Faculty of Tunis, Homeostasis and Cell Dysfunction Unit Research, 15 Djebel Lakhdhar Street 1007, Tunis, Tunisia

Corresponding Author:
Dr. Halioui-Louhaichi Sonia
Pediatric Department of Mongi Slim Hospital La Marsa
Tel: 0021622130024
E-mail: [email protected]

Received February 09, 2016; Accepted March 07, 2016; Published Date: March 13, 2016

Citation: Sonia HL, Ali M, Yousr D, Wiem B, Anies H, et al. (2016) Serum Vitamin D Level in Children with and without Type 1 Diabetes Mellitus. J Diabetes Metab 7:655. doi:10.4172/2155-6156.1000655

Copyright: © 2016 Sonia HL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



For years, vitamin D has been associated to many immune disorders. Several studies have shown association between low serum 25 OH vitamin D and type 1 diabetes mellitus (T1DM). Objective: To compare 25 hydroxy vitamin D (25 OHD) level in T1DM patients to non-diabetic children hospitalized or seen in emergency for other diseases at the same period. Methods: It was a case-control study including 29 patients with T1DM and 28 non - diabetic control children. They were comparable in age, gender, weight, length, BMI and season of blood sampling. Epidemiological and clinical data were collected and 25OHD serum level was measured with a radioimmunoassay kit. Results: 25OHD level was significantly lower in diabetic patients (mean: 19.62 ng/ml, range 15-26 ng/ml) than in control patients (24.64 ng/ml, 20-28 ng/ml), p=0.00. All participants (T1DM patients and controls) had inadequate levels of vitamin D. Conclusion: Children with T1DM have lower vitamin D levels than control group.


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