alexa Severe Nervous System Damage in Long-Term Professional Exposure to Phthalates
ISSN: 2161-0495

Journal of Clinical Toxicology
Open Access

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Case Report

Severe Nervous System Damage in Long-Term Professional Exposure to Phthalates

Włodzisław Kuliński*

Department of Rehabilitation, Warsaw Division of Physical Medicine, Military Medical Institute, Jan Kochanowski University, Kielce, Poland

*Corresponding Author:
Włodzisław Kuliński
Department of Rehabilitation, Warsaw Division of Physical Medicine, Military Medical Institute
Jan Kochanowski University, ul. Karola Miarki 11B 01-496, Warszawa, Kielce, Poland
Tel: +0048503486095

Received date: December 28, 2016; Accepted date: March 15, 2017; Published date: March 20, 2017

Citation: Kulinski W (2017) Severe Nervous System Damage in Long-Term Professional Exposure to Phthalates. J Clin Toxicol 7:342. doi: 10.4172/2161-0495.1000342

Copyright: © 2017 Kuliński W. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



This paper presents a case of a 37-year-old male patient who suffered from very severe nervous system damage with tetraparesis after having used a paint thinner containing diisononyl phthalate at work for more than ten years. Brain MRI revealed scattered focal lesions in both cerebral hemispheres, typical of cytotoxic oedema. A follow-up examination conducted after 2 years showed persistent lesions and more severe cortical atrophies. Decreased cognitive function and operating memory disturbances were also observed in the patient. His mental processes display features of sluggishness and lack flexibility. Clinical presentation of the patient indicates severe nervous system damage in long-term contact with phthalates.


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