Should Medications be Coadministered with Albumin in Hypoalbuminemic PatientsSerlemitsos Day M1*, Ellington K1, Akalu A1 and Kimberly NU2
- *Corresponding Author:
- Serlemitsos Day M
Howard University College of Pharmacy
Washington, DC, USA
Tel: (202) 806-4919
E-mail: [email protected]
Received date: November 01, 2016; Accepted date: December 05, 2016; Published date: December 13, 2016
Citation: Serlemitsos Day M, Ellington K, Akalu A, Kimberly NU (2017) Should Medications be Coadministered with Albumin in Hypoalbuminemic Patients. J Pharma Care Health Sys 4:167. doi: 10.4172/2376-0419.1000167
Copyright: © 2016 Serlemitsos Day M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Protein binding significantly influences pharmacokinetic properties of drug distribution. Albumin accounts for approximately 60% of the total plasma protein by mass, thereby making it the major protein in the body. Hypoalbuminemia, a type of hypoproteinemia, is a condition of abnormally low blood albumin levels. Hypoaluminemia causes pharmacokinetic issues in regards to dosing a patient's medication. The purpose of this paper is to review the role of the coadministration of albumin in hypoalbuminemic patients to optimize pharmacotherapy.