alexa Silymarin in Dermatology: A Brief Review
ISSN: 2376-0427

Dermatology and Dermatologic Diseases
Open Access

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Previously: Journal of Pigmentary Disorders

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Review Article

Silymarin in Dermatology: A Brief Review

Shadi Mehraban1 and Amir Feily2*
1Medical Student, Jahrom university of Medical Sciences, Jahrom, Iran
2Department of Dermatology, Jahrom University of Medical Sciences, Jahrom, Iran
Corresponding Author : Amir Feily
Department of Dermatology
Honari Clinic, Motahari Street, Jahrom, Iran
Tel: 00989177204638
E-mail: [email protected]
Received July 21, 2014; Accepted August 02, 2014; Published August 04, 2014
Citation: Mehraban S, Feily A (2014) Silymarin in Dermatology: A Brief Review. pigmentary disorders 1:125. doi:10.4172/2376-0427.1000125
Copyright: © 2014 Mehraban S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Background: Silymarin, a flavonoid with antioxidant activities and extracted from milk thistle (Silybum marianum), previously used for its liver protection activity has been recently tested for dermatologic disorders Objectives: Our purpose was to summerize all the dermatologic oriented in vitro and in vivo experiments and clinical trials on silymarin. Methods: A systematic review of the literature was conducted to investigate all the available data and summarize all the clinical trials, case reports and original articles on silymarin. Two major databases (PubMed and Google Scholar) were searched. Results: We have gone over about 26 articles. Silymarin, has been shown to have anticarcinogenic effects against ultraviolet radiation which makes it an ideal agent for supplementing sunscreens protection. Silymarin has also been effective in overcoming rosacea, melasma, vitiligo and psoriasis. Conclusions: Even though there are some promising results with silymarin in dermatologic conditions but its human efficacy is not sufficiently explored as yet.

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