alexa Single-Walled-Carbon-Nanotube-Based Field-Effect Transistors with Biosensing Functions for Prostate-Specific-Antigen | OMICS International | Abstract
ISSN: 0975-0851

Journal of Bioequivalence & Bioavailability
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Research Article

Single-Walled-Carbon-Nanotube-Based Field-Effect Transistors with Biosensing Functions for Prostate-Specific-Antigen

Hu Yan*, Yuta Mochizuki, Toshihiko Jo and Hidenori Okuzaki*

Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, 4-4-37 Takeda, Kofu 400-8511, Japan

*Corresponding Author:
Dr. Hu Yan, Ph.D.,
Associate Professor
Interdisciplinary Graduate School of Medicine and Engineering
University of Yamanashi, 4-4-37 Takeda
Kofu 400-8511, Japan
E-mail: [email protected]

Dr. Hidenori Okuzaki, Ph.D.,
Associate Professor
Interdisciplinary Graduate School of Medicine
and Engineering University of Yamanashi, 4-4-37 Takeda
Kofu 400- 8511, Japan
E-mail: [email protected]

Received Date: January 21, 2011; Accepted Date: April 25, 2011; Published Date: May 25, 2011

Citation: Yan H, Mochizuki Y, Jo T, Okuzaki H (2011) Single-Walled-Carbon- Nanotube-Based Field-Effect Transistors with Biosensing Functions for Prostate- Specific-Antigen. J Bioequiv Availab 3: 069-071. doi: 10.4172/jbb.1000061

Copyright: © 2011 Yan H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Single-walled carbon nanotube (SWCNT) field-effect transistors (FETs) were fabricated on strontium titanate (SrTiO3) substrate through a wet-process by using amide-functionalized SWCNT. The SWCNT-FET exhibited good gate-modulation for drain current at low operating voltages (-3 V). The hole mobility was 0.19 cm2/Vs with an on/ off current ratio of 1.3. After immobilization of prostate-specific-antigen (PSA) antibody the SWCNT-FET clearly responded against the PSA. The drain current at -3 V of both drain and gate voltage almost linearly increased with increasing the concentration of the PSA.

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