SiRNA Scanner - A Fuzzy Logic Based Tool for Small Interference RNA Design
Vijayakumar Saravanan, Piramanaygam Shanmughavel*
DBT Bioinformatics Facility, Department of Bioinformatics, Bharathiar University, Coimbatore - 641046, Tamilnadu, India
- *Corresponding Author:
- Dr. Piramanaygam Shanmughavel
DBT-Bioinformatics Infrastructure Facility
Department of Bioinformatics, Bharathiar University
Coimbatore,Tamil Nadu - 641046. India
E-mail : [email protected]
Received Date: May 20, 2008; Accepted Date: June 18, 2008; Published Date: June 19, 2008
Citation: Vijayakumar S, Piramanaygam S (2008) SiRNA Scanner - A Fuzzy Logic Based Tool for Small Interference RNA Design. J Proteomics Bioinform 1:154-160. doi:10.4172/jpb.1000021
Copyright: © 2008 Vijayakumar S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The discovery of short interfering RNA has admitted the development of facile regulated methods for disruption of gene expression. However, this method continues to grow in popularity, designing effective siRNA can be demanding. So we have developed siRNA Scanner, a siRNA selection program that automatically selects Small Interfering RNA from the given RNA sequences. siRNA Scanner uses a fuzzy logic-based system to calculate siRNA qualities. This program is fully built in Practical Extract Report Language (PERL 22.214.171.124 Build 820) and accessible in a command line interface. siRNA Scanner's high performance, minimal user interaction, and its fast algorithm, make this program useful for selecting Small Interfering RNA for gene expression studies.