alexa Sjogren's Syndrome with Polyserositis, Gastrointestinal Findings and Ascending Aortic Aneurysm
ISSN: 2329-9495

Angiology: Open Access
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Case Report

Sjogren's Syndrome with Polyserositis, Gastrointestinal Findings and Ascending Aortic Aneurysm

Gulumser Heper, MD1*, Suha Cetin, MD1, Kemal Una1, MD2, Salih Salihi, MD3, Basak Bostancı, MD4, Murat Korkmaz, MD5

1Department of Cardiology, Okan University Medical Faculty, Istanbul, Turkey

2Department of Nuclear Medicine, Okan University Medical Faculty, Istanbul, Turkey

3Department of Cardiovascular Surgery, Okan University Medical Faculty, Istanbul, Turkey

4Department of Ophthalmology, Okan University Medical Faculty, Istanbul, Turkey

5Department of Gastroenterology, Okan University Medical Faculty, Istanbul, Turkey

*Corresponding Author:
Gulumser Heper
Department of Cardiology, Okan University
Aydınlı Cad No:2 34947 İçmeler, Tuzla, Istanbul, Turkey
Tel: 00905325252999
E-mail: [email protected]

Received date: 27 April, 2017; Accepted date: 05 May, 2017; Published date: 09 May, 2017

Citation: Heper G, Cetin S, Unal K, Salihi S, Bostanci B, Korkmaz M (2017) Sjögren’s Syndrome with Polyserositis, Gastrointestinal Findings and Ascending Aortic Aneurysm. Angiol 5:193. doi: 10.4172/2329-9495.1000193

Copyright: © 2017 Heper G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Sjögren’s syndrome (SS) is an autoimmune disease with glandular and extraglandular manifestations. Pleural and pericardial effusions in association with SS are rare. Similarly, ascites is rare and it can occur in SS when combined with primary biliary cirrhosis (PBC). Inflammatory Abdominal Aortic Aneurysm together with SS has been described only in one case. We report herein the case of a 70-year-old man with SS presenting with polyserositis (pleural and pericardial effusion and ascites) and gastrointestinal manifestations (atrophic gastritis and candida esophagitis) and ascending aorta aneurysm. SS was diagnosed based on xerophthalmia, xerostomia, extraglandular manifestations, positive results for the Schirmer test, ocular surface staining score, histopathologic examination of labial buccal mucosa revealing focal lymphocytic sialadenitis and unstimulated salivary flow rate. The only positive autoantibody was against smooth muscle cells (ASMA). We thought that pleural, pericardial effusions, ascites, gastrointestinal findings and ascending aortic aneurysm may be related with autoimmunological inflammation of SS. To evaluate the extent of aortic vasculitis, we performed a whole body 18-Fluorodeoxyglucosepositron emission tomography (FDG-PET) and showed increased uptake of FDG in aneurysmal section of the ascending aorta. Treatment with high dose corticosteroid was proved to be successful in both clinically and laboratory.

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