Journal of Clinical Case Reports

Soft Tissue Rosai-Dorfman Disease in a 77-Year-Old Female

Abstract

Edgar Zamora and Peter Kragel

Rosai-Dorfman disease is a histiocytic disorder that is most common in children and young adults of African
descent which typically presents as painless massive cervical lymphadenopathy. The purpose of this article is to
report a case of Rosai-Dorfman disease in a 77-year-old woman who presented with a large subcutaneous mass
in her lower left abdomen. Microscopic examination revealed diagnostic features of Rosa-Dorfman disease. This
uncommon disorder may involve lymph nodes and other organs, but rarely involves and presents as a soft tissue
tumor. Clinical observation is the usual treatment, and correct diagnosis is important to avoid unnecessary therapy.