Soy Isoflavonoids as Nutraceutical for Human Health: An Update
Murlidhar Meghwal* and Chandan Kumar Sahu
Food Science and Technology Division, Centre for Emerging Technologies, Jain University, Karnataka, India
- *Corresponding Author:
- Murlidhar Meghwal
Food Science and Technology Division
Centre for Emerging Technologies, Jain University
Jain Global Campus, Jakkasandra - 562112
Kanakapura Main Road, Ramanagara Dist, Karnataka, India
Tel: 91 9739204027
E-mail: [email protected]
Received Date: December 05, 2014; Accepted Date: January 28, 2015; Published Date: February 03, 2015
Citation: Meghwal M, Sahu CK (2015) Soy Isoflavonoids as Nutraceutical for Human Health: An Update. J Cell Sci Ther 6:194. doi: 10.4172/2157-7013.1000194
Copyright: © 2015 Meghwal M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Isoflavones are the most abundant phytoestrogen in soybeans which are structurally similar with 17 β-estradiol. The antioxidant property of genistein and daidzein are well established in different experimental and clinical models. Isoflavones compounds have been found effective in the management of diabetes. It reduces low-density lipoprotein and triglycerides and hence minimizes the risk of coronary heart disease. Soy isoflavones was found useful for treatment of osteoporosis by inhibiting tyrosine kinase. In soy isoflavones, genistein is effective in the treatment of cancer by acting on androgen receptor and inhibiting tyrosine kinases. In this update many nutraceuitical and medicinal uses and applications of soy isoflavones have been investigated such as treatment and prevention of cardiovascular diseases, cholesterol lowering, osteoporosis, diabetes, cancer, cognitive decline, and menopausal symptoms.