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Spasmodic Dysphonia and Thalamic Deep Brain Stimulation: Long-term Observations, Possible Neurophysiologic Mechanism and Comparison of Unilateral Versus Bilateral Stimulation | Abstract
ISSN: 2155-9562

Journal of Neurology & Neurophysiology
Open Access

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Research Article

Spasmodic Dysphonia and Thalamic Deep Brain Stimulation: Long-term Observations, Possible Neurophysiologic Mechanism and Comparison of Unilateral Versus Bilateral Stimulation

Mark K. Lyons1*, Orland K. Boucher1 and Virgilio G. H. Evidente2

1Departments of Neurological Surgery, Mayo Clinic, Arizona

2Department of Neurology, Mayo Clinic, Arizona

Corresponding Author:
Dr. Mark K. Lyons, MD
Associate Professor and Chair
Department of Neurological Surgery
Mayo Clinic Arizona, 5777 East Mayo
Boulevard, Mayo Clinic Hospital 5 East
Phoenix, AZ 85054
Tel: 480-342-3616
Fax: 480-342-3699
E-mail: [email protected]

Received date: October 13, 2010; Accepted date: December 28, 2010; Published date: December 30, 2010

Citation: Lyons MK, Boucher OK, Evidente VGH (2010) Spasmodic Dysphonia and Thalamic Deep Brain Stimulation: Long-term Observations, Possible Neurophysiologic Mechanism and Comparison of Unilateral Versus Bilateral Stimulation. J Neurol Neurophysiol 1:106. doi:10.4172/2155-9562.1000106

Copyright: © 2010 Lyons MK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Abstract

The co-existence of essential tremor and spasmodic dysphonia has been reported in the literature. Spasmodic dysphonia is a primary focal dystonia manifested by loss of control of the vocal muscles during speech secondary to laryngeal muscle spasms. The pathophysiology is not well understood. Deep brain stimulation surgery (DBS) for other focal dystonias has been well reported. Voice and laryngo-videostroboscopic examinations can aid in confirmation of spasmodic dysphonia as opposed to voice tremor due to the underlying essential tremor. We report the long term follow up of a patient who underwent bilateral thalamic deep brain stimulation surgery for essential tremor and coincident spasmodic dysphonia, and report the effects of unilateral versus bilateral stimulation on her dysphonia. The topic literature is reviewed and the potential neuroanatomical pathophysiologic mechanisms of this finding are also discussed. .

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