alexa Spontaneous Bacterial Peritonitis and Bacteremia in Patients with Liver Cirrhosis | OMICS International | Abstract
ISSN: 2161-0703

Journal of Medical Microbiology & Diagnosis
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Review Article

Spontaneous Bacterial Peritonitis and Bacteremia in Patients with Liver Cirrhosis

Toru Shizuma*

Department of Physiology, School of Medicine, Tokai University, Japan

*Corresponding Author:
Toru Shizuma
Department of Physiology
School of Medicine, Tokai University
143, Shimokasuya, Isehara, Kanagawa, 259-1193, Japan
Tel: +81-0463-93-1121
Fax: +81-0463-93-6684
E-mail: [email protected]

Received Date: January 04, 2014; Accepted Date: June 27, 2014; Published Date: June 30, 2014

Citation: Shizuma T (2014) Spontaneous Bacterial Peritonitis and Bacteremia in Patients with Liver Cirrhosis. J Med Microb Diagn 3:142. doi: 10.4172/2161-0703.1000142

Copyright: © 2014 Shizuma T. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Abstract

Abstract
Patients with Liver Cirrhosis (LC) are at high risk of developing bacterial infections.

Pathological

bacterial translocation has been implicated as an important cause of bacterial infection in patients with LC, and Spontaneous Bacterial Peritonitis (SBP) and bacteremia are common and often fatal bacterial infections in these patients. Moreover, the incidence of hepatorenal syndrome is associated with bacterial infections such as SBP; in addition, the syndrome is often fatal in

patients

with LC. The frequency of isolation of multidrug-resistant (MDR) organisms in patients with LC and bacterial infections has been reported to be increasing in recent years, and infections caused by MDR

organisms

appear to be associated with poor prognoses. However, further research is required to better understand bacterial infections in the setting of LC because there remain unresolved problems related to this issue. This review summarizes the frequency, diagnoses, causative organisms, prognoses, and treatment of SBP and bacteremia in patients with LC.

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