alexa Standardized Low Resolution Electromagnetic Tomography (s_LORETA) is a Sensitive Indicator of Protracted Neuropsychological Impairments Following “ Mild ” (Concussive) Traumatic Brain Injury
ISSN: 2155-9562

Journal of Neurology & Neurophysiology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Standardized Low Resolution Electromagnetic Tomography (s_LORETA) is a Sensitive Indicator of Protracted Neuropsychological Impairments Following “ Mild ” (Concussive) Traumatic Brain Injury

Paula L Corradini and Michael A Persinger*

Departments of Psychology and Biology, Laurentian University, Sudbury, Ontario, Canada

Corresponding Author:
Michael A Persinger
Clinical Neuroscience Laboratory
Behavioural Neuroscience Program
Departments of Psychology and Biology
Laurentian University, Sudbury
Ontario, Canada P3E 2C6
Tel: 01-705-675-4824
Fax: 01-705-671-3844
E-mail: [email protected]; [email protected]

Received date: October 31, 2013; Accepted date: November 26, 2013; Published date: December 04, 2013

Citation: Corradini PL, Persinger MA (2013) Standardized Low Resolution Electromagnetic Tomography (s_LORETA) is a Sensitive Indicator of Protracted Neuropsychological Impairments Following “Mild” (Concussive) Traumatic Brain Injury. J Neurol Neurophysiol 4:176. doi:10.4172/2155-9562.1000176

Copyright: © 2013 Corradini PL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Background: Differentiation of patients who have sustained a mild TBI and who show continued difficulties with adaptation is a major clinical challenge and a time-consuming process when classical neuropsychological testing is involved. LORETA (Low Resolution Electromagnetic Tomography) was employed to discern its sensitivity for differentiating the regions of the cerebrum for patients who exhibited continued difficulties with adaptation and showed either no or formal neuropsychological impairment years after the injury. Methods: The quantitative electroencephalographic data for total of 14 patients who had sustained a mild TBI and who either displayed moderately-severe neuropsychological impairment (n=7) or did not (n=7) according to the results of a standardized battery were analyzed by s_LORETA software. The centroid Talairach (X,Y,Z) components for each major frequency band that were significantly different between the two populations were computed. Results: Averaged s_LORETAs demonstrated that the group of patients who displayed formal moderate-severe neuropsychological impairments more than five years after the injury displayed differential power values compared to the group of patients who also sustained a TBI but exhibited no formal impairment within regions that were consistent with the residual subjective symptoms. The s_LORETA analyses, including data collection, required less than 1 hr. Conclusion: A 30 minute sample of QEEG data when applied to s_LORETA software can reveal the general regions of the cerebrum that remain anomalous for years after the initial injury. Employment of this technology could be more efficient and provide greater precision for the strategic interventions that could facilitate the patients’ adaptation.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version