alexa Stem Cell in Lingual Epithelia and Papillae | OMICS International| Abstract
ISSN: 2161-0444

Medicinal Chemistry
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  • Review Article   
  • Med chem (Los Angeles) 2018, Vol 8(5): 118
  • DOI: 10.4172/2161-0444.1000503

Stem Cell in Lingual Epithelia and Papillae

Feng Li*
Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China
*Corresponding Author : Feng Li, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China, Tel: 8613651824980, Email: [email protected]

Received Date: May 04, 2018 / Accepted Date: May 08, 2018 / Published Date: May 15, 2018


In mammalian tongue, all the compartments of the lingual epithelium are turned over throughout adult life. There is a continual requirement for proliferation to replace cells lost by differentiation within each compartment. In contrast to remarkably elucidating to the molecular basis for taste perception, too little is known about the mechanism of lingual epithelium and papillae. In this article, we briefly summarize what is known about the different stem cell compartments in lingual epithelium and papillae, and discuss the evidence for existence of stem cell in lingual epithelium and taste bud. We then consider a new model of homeostasis in lingual epithelium and papillae, in which tissue maintenance depends on multiple-stem cell population. Problems revealed by the application of epigenetic marker are also discussed.

Keywords: Stem cell; Lingual epithelia; Taste bud; Papillae; Cell genesis

Citation: Li F (2018) Stem Cell in Lingual Epithelia and Papillae. Med Chem (Los Angeles) 8: 118-126. Doi: 10.4172/2161-0444.1000503

Copyright: © 2018 Li F. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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