alexa Stem/progenitor Cell Based Therapies for Repair of Myoc
ISSN: 2161-1076

Surgery: Current Research
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article

Stem/progenitor Cell Based Therapies for Repair of Myocardial Infarction: Current Developments in Methods of Cell Delivery

Jialiang Liang and Yigang Wang*

Departments of Pathology and Laboratory Medicine, College of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA

*Corresponding Author:
Yigang Wang, M.D, Ph.D
Associate Professor
Department of Pathology and Laboratory Medicine
College of Medicine, University of Cincinnati Medical Center
231 Albert Sabin Way, Cincinnati, Ohio, USA
Tel: 513-558-5798
E-mail: [email protected]

Received date: February 16, 2013; Accepted date: May 30, 2013; Published date: June 07, 2013

Citation:Liang J, Wang Y (2013) Stem/progenitor Cell Based Therapies for Repair of Myocardial Infarction: Current Developments in Methods of Cell Delivery. Surgery Curr Res 3:131. doi: 10.4172/2161-1076.1000131

Copyright: © 2013 Liang J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Regenerative medicine offers hope for patients with myocardial infarction (MI). A good deal of clinical evidence shows that the transplantation of stem/progenitor cells from numerous sources can produce significant protective effects in the injured heart, such as enhanced perfusion and contractility. The therapeutic effects of transplanted cells depend on appropriate delivery into the damaged area of the heart. Thus, the method of cell delivery is an important aspect of stem/progenitor cell based therapy, because it affects the fate of transplanted cells and consequently determines the clinical outcome. It is still difficult to determine the optimal cell delivery strategy for MI treatment from the current preclinical and clinical studies, although cell injections have been widely used in the delivery of various types of progenitor cells in clinical trials. Additionally, cell patch engineering has emerged as one of the most promising new approaches. This review summarizes the methods, feasibility, safety, efficacy, and advancements of these two approaches from recent publications. The combined use of various delivery approaches with stem/ progenitor cell transplantation emerges as an important administration method in tissue engineering to promote cardiac regeneration.

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords