alexa Stenting of Left Main Coronary Artery Stenosis: Data to
ISSN: 2329-9517

Journal of Cardiovascular Diseases & Diagnosis
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Review Article

Stenting of Left Main Coronary Artery Stenosis: Data to Clinical Practice

Debabrata Dash* and Shao-Liang Chen
Fortis Raheja Hospital, Raheja Rugnalaya Marg Mahim (West), 400016 Mumbai, India
Corresponding Author : Debabrata Dash
Senior Consultant Interventional Cardiologist
Fortis Raheja Hospital, Raheja Rugnalaya Marg Mahim (West)
400016 Mumbai, India
Tel: +91-9833928466
E-mail: [email protected]
Received: July 15, 2015; Accepted: September 15, 2015; Published: September 17, 2015
Citation: Dash D, Chen SL (2015) Stenting of Left Main Coronary Artery Stenosis: Data to Clinical Practice. J Cardiovasc Dis Diagn 3:222.doi:10.4172/2329-9517.1000222
Copyright: © 2015 Dash D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

For several decades, coronary artery bypass grafting (CABG) has been considered as the gold standard treatment of unprotected left main coronary artery (LMCA) disease. However, because of large vessel caliber and anatomic accessibility, percutaneous coronary intervention (PCI) for LMCA has been attractive option for interventional cardiologists. With the marked improvement in technique and technology, PCI has been shown to be feasible for patients with unprotected LMCA stenosis. The recent introduction of drug-eluting stents (DESs), together with advances in pre procedural and post procedural adjunctive pharmacotherapies, has improved outcomes of PCIs of these lesions. The available current evidence comparing efficacy and safety of PCIs using DES and CABG revealed comparable results in terms of safety and a lower need for repeat revascularization for CABG. Still the management can be challenging in high risk anatomic subsets involving LMCA bifurcation lesions and, therefore, an integrated approach combining advanced devices, tailored techniques, adjunctive support of physiologic evaluation, and adjunctive pharmacologic agents should be reinforced to improve clinical outcome.

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