Steroid Therapy in Oral Lichen Planus
Oral Pathology and Medicine, Ministry of Health, Giza, Egypt
- *Corresponding Author:
- Alerraqi E
Oral Pathology and Medicine
Ministry of Health
E-mail: [email protected]
Received date: April 30, 2016; Accepted date: May 25, 2016; Published date: May 31, 2016
Citation: Alerraqi E (2016) Steroid Therapy in Oral Lichen Planus. J Steroids Hormon Sci 7:173. doi:10.4172/2157-7536.1000173
Copyright: © 2016 Alerraqi E, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Oral lichen planus (OLP) is a chronic inflammatory disease characterized by cellular-mediated inflammatory reactions which render apoptotic epithelial cells and degeneration of the basal epithelial layer. Eighteen volunteering cases of OLP were scheduled, after getting their informed consents, to be reported in this study. All of them were diagnosed histologically. The diagnosis was confirmed via immunofluorescence. Another incisional sample was scheduled after finishing the recruited treatment. The patient histological findings were contrasted, before and after treatment, to ten cases of non-lesional archival cases of oral mucosa as a control group. Results revealed no difference in the response to the pharmaceutical form of steroids used in treating OLP. Although steroid therapy is the mainstay treatment of OLP, adjuvant treatment modalities should be recruited for improving the healing process.