Stress, Adaptogens and Their Evaluation: An Overview
Arunabha Ray*, Kavita Gulati and Rashmi Anand
Department of Pharmacology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi-110007, India
- Arunabha Ray
Department of Pharmacology
Vallabhbhai Patel Chest Institute
University of Delhi, Delhi-110007, India
Tel: 91-11-27402403, +919818037595
E-mail: [email protected]
Received Date: January 19, 2016; Accepted Date: March 9, 2016;Published Date: March 12, 2016
Citation: Ray A, Gulati K, Anand R (2016) Stress, Adaptogens and Their Evaluation: An Overview. J Pharma Reports 1:110. doi:10.4172/jpr.1000110
Copyright: © 2016 Ray A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Stress is any physical, psychological and/or environmental stimulus capable of altering physiological homeostasis, and the ability to cope with such stressful stimuli is a crucial determinant of health and disease. Stress itself is a defense response of an organism to external factors activating several protective mediators but prolonged stress can be detrimental and have deleterious effects on the biological system. Stress in its different forms is capable of precipitating a variety of pathophysiological states and almost all organs/systems have been implicated. Conventional therapies though effective have a plethora of adverse effects and hence there is a dire need for developing better therapeutic options/strategies. The term adaptogen is used primarily to describe agents from herbal sources, which increase the resistance to aversive inputs and result in overall protective effects during stress. In recent years, adaptogens have gained considerable attention because of their safety, cost effectiveness and efficacy in stress modulating effects which could improve the quality of life in both diseased and healthy persons. This review will attempt to summarize and critically analyze the recent concepts in the area of such adaptogens and their evaluation methodologies.