alexa Stress in the Patella Following Autologous Chondrocyte Implantation - A Finite Element Study
ISSN: 0974-7230

Journal of Computer Science & Systems Biology
Open Access

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Research Article

Stress in the Patella Following Autologous Chondrocyte Implantation - A Finite Element Study

Walker RW1, Cheah K2, Ingle P1 and Mootanah R1*

1Medical Engineering Research Group, Department of Engineering and the Built Environment, Faculty of Science and Technology, Anglia Ruskin University, Chelmsford, Essex, CM1 1SQ, UK

2Orthopaedic Department, Ramsay Springfield Hospital, Chelmsford, Essex, CM1 7GU, UK

*Corresponding Author:
Rajshree Mootanah
Medical Engineering Research Group
Department of Engineering and the Built Environment
Faculty of Science and Technology, Anglia Ruskin University
Chelmsford, Essex, CM1 1SQ, UK
Tel:(44) 1245 683909
E-mail: [email protected]

Received date: August 29, 2013; Accepted date: October 18, 2013; Published date: October 25, 2013

Citation: Walker RW, Cheah K, Ingle P, Mootanah R (2013) Stress in the Patella Following Autologous Chondrocyte Implantation - A Finite Element Study. J Comput Sci Syst Biol 6:305-310. doi:10.4172/0974-7230.1000126

Copyright: © 2013 Walker RW, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License,which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Bovine patella cartilage shows signs of damage and cell death when subjected to a compressive cyclic load of 6 MPa, which results in a shear stress of 5.6 MPa. The aim of this research was to investigate the effect of activities of daily living (descending stairs, bicycling and deep flexion) on the contact stresses in the patellofemoral compartment following an articular chondrocyte implantation (ACI). A finite element (FE) model of the patellar femoral joint was created and dynamic non-linear analyses were carried out for this purpose. A shear stress of 5.6 MPa was used as the threshold that cartilage can tolerate without resulting in damage. The FE model was verified numerically. Our results show that, for a 70 kg individual at 50% recovery, (i) contact stress in the patella is 11% higher than that in the femur; (ii) shear stress in the host cartilage reaches 4.75 MPa at 50° of flexion; (iii) shear stress in the patella host cartilage is twice that in a healthy cartilage during deep flexion approaching 70°; (iv) maximum shear stress value was 2.75 MPa during cycling at 60% load; (v) stress shielding still occurs through the host cartilage even when the implanted cartilage reaches 97.5% the Young’s modulus of a healthy cartilage. Based on these results, (i) using an exercise bicycle is recommended for rehabilitation; (ii) deep knee flexion should be avoided; (iii) obese people with a BMI of over 42 kg/m2 should not undertake vigorous weight-bearing exercises involving deep knee flexion.

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