alexa Study of Conserved Domain across Divergent Phylogenetic
ISSN: 2329-9002

Journal of Phylogenetics & Evolutionary Biology
Open Access

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Research Article

Study of Conserved Domain across Divergent Phylogenetic Lineages of Long Neurotoxin from Genus Naja (Elapidae Family)

Sherkhane AS1, Waghmare Somnath2 and Gomase VS2*
1The Global Open University, Nagaland
2Department of Zoology, Nowrosjee Wadia College of Arts and Science, Pune-1, MS, India
Corresponding Author : Gomase VS
Department of Computer Science and IT
Dr. Babasaheb Ambedkar Marathwada University
Aurangabad, 431004, MS, India
Tel: 91-9987770696
E-mail: [email protected]
Received May 16, 2014; Accepted June 09, 2014; Published June 16, 2014
Citation: Sherkhane AS, Somnath W, Gomase VS (2014) Study of Conserved Domain across Divergent Phylogenetic Lineages of Long Neurotoxin from Genus Naja (Elapidae Family). J Phylogen Evolution Biol 2: 127. doi:10.4172/2329-9002.1000127
Copyright: © 2014 Sherkhane AS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Naja are a toxic genus of Elapids family in the old world. Long neurotoxins are mixtures of peptides, enzymes that interfere with the normal function of the nervous system and potently block α7 homo-oligomeric neuronal AChRs causing paralysis. The aim of the present study is to identify the origin of long neurotoxin, multiple sequences analysis for prediction of structure and function of neurotoxin and observing the conserved pattern of amino acid residues and to construct the phylogenetic tree for organizing evolutionary history of Naja genus from Elapidae family.

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