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ISSN: 2161-0444

Medicinal Chemistry
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Research Article

Study of Phenolic Composition and Biological Activities Assessment of Olive Leaves from different Varieties Grown in Tunisia

Myriam Ben Salah1,2*, Hafedh Abdelmelek1 and Manef Abderraba2

1Faculté des Sciences de Bizerte, Laboratoire de Physiologie Intégrée, 7021Jarzouna, Tunisia

2Institut Préparatoire aux Etudes Scientifiques et Techniques, Unité de Recherche Physico-Chimie-Moléculaire, La Marsa

*Corresponding Author:
Myriam Ben Salah
Faculté des Sciences de Bizerte
Laboratoire de Physiologie Intégrée
7021 Jarzouna, Tunisia
Fax: +216 72590566
E-mail: [email protected]

Received date: May 25, 2012; Accepted date: August 13, 2012; Published date: August 15, 2012

Citation: Salah MB, Abdelmelek H, Abderraba M (2012) Study of Phenolic Composition and Biological Activities Assessment of Olive Leaves from different Varieties Grown in Tunisia. Med chem 2:107-111. doi:10.4172/2161-0444.1000124

Copyright: © 2012 Salah MB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


In the present study, olive leaves of eight varieties were investigated for the total phenol and flavonoid content, for the major compound and for the in vitro antioxidant properties. The different varieties showed a high content of polyphenol and flavonoid. Oleuropein was the major compound of the leaf extract for all varieties. Also, olive leaves extract exhibited a good antioxidant activity and a reduced power, each variety showed its own feature. A significant negative correlation between anti-radical activities and oleuropein content was observed only for four varieties (r = - 0.94). The high oleuropein content and the important antioxidant activities of olive leaves extract could be useful sources for industrial extraction and pharmacological application in the promotion of health and prevention of damages caused by radicals.


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