alexa Study of the Synergistic Effect of Antibiotics and Plan
e-ISSN:2320-1215 p-ISSN: 2322-0112

Research & Reviews in Pharmacy and Pharmaceutical Sciences
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Short Communication

Study of the Synergistic Effect of Antibiotics and Plant Extracts Against Clinical Staphylococcus aureus Strains.

Ibrahim TA1*, Fagbohun ED2, and Olalumade BB1

1Department of Food Science and Technology, Rufus Giwa Polytechnic, Owo, Ondo State, Nigeria

2Department of Microbiology, Ekiti State University,Ado Ekiti, Nigeria

*Corresponding Author:
Ibrahim TA
Department of Food Science and Technology
Rufus Giwa Polytechnic, Owo, Ondo State, Nigeria

Received: 14/10/2013 Accepted: 22/11/2013



The synergistic anti-bacterial action of two plants (Eucalyptus and Thuja) extracts on plasma coagulation by staphylococcus aureus and the effect of conventional chemotherapy combined with plant extracts below the MIC. Coagulation was inhibited in plasma containing (10, 20, 50,70 and 100mg\L)for both extracts. The MICs of ampicillin and ciprotab for S.aureus markedly reduced from (0.25, 0.5 and 1mg\L) of the four resistant strains to 0.06mg\L in Muller Hinton agar (MHA) plates with 20mg\L Eucalyptus extract and 50mg\L Thuja extract. The results suggest that T. catappa and E. camaldulensis extracts can be used in treating diseases caused by the test organisms.


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