alexa Subcutaneous Malignant Melanoma developing in Congenita
ISSN: 2376-0427

Dermatology and Dermatologic Diseases
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Previously: Journal of Pigmentary Disorders

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Case Report

Subcutaneous Malignant Melanoma developing in Congenital Giant Naevus with Complete Spontaneous Regression of Superficial Dermo-Epidermal Part:A Case Report

Sohini Roy1, Debarati Chattopadhyay2, Kaushik Dewan3, Keya Sarkar Biswas4 and Uttam Kumar Nath4*
1N.R.S Medical College, Kolkata, India
2Institute of Post Graduate Medical Education and Research, Kolkata, India
3School of Tropical Medicine, Kolkata, India
4Institute of Haematology and Transfusion Medicine, Medical College, Kolkata, India
Corresponding Author : Uttam Kumar Nath
Associate Professor
Institute of Haematology and Transfusion Medicine
Medical College, Kolkata, India
E-mail: [email protected]
Received July 01, 2015; Accepted July 04, 2015; Published July 14, 2015
Citation: Roy S, Chattopadhyay D, Dewan K, Biswas KS, Nath UK (2015) Subcutaneous Malignant Melanoma developing in Congenital Giant Naevus with Complete Spontaneous Regression of Superficial Dermo-Epidermal Part: A Case Report. Pigmentary Disorders 2:196. doi:10.4172/2376-0427.1000196
Copyright: © 2015 Roy S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Giant congenital melanocytic nevi a ≥ 20 cm is rare in adolescents and adults. Here we present a case of subcutaneous melanoma developing in congenital giant naevus with complete regression of superficial dermoepidermal part. A 17 yr old girl presented with a painless and gradually increasing swelling in her right temporal region on pre-existing giant congenital menocytic naevus (GCMN) on right hemiface. FNAC proved the case as malignant melanoma of temporal region with metastatic deposit in cervical lymph node. On histopathological examination it was found that the melanoma arising deep in the subcutaneous tissue with extensive involvement of deeper structures, extensive metastasis of cervical lymph nodes, salivary glands, deeper soft tissues with spontaneous regression of superficial epidermal and dermal part. Though regression is seen in melanomas, spontaneous regression has been mostly seen in melanomas with only intraepidermal component.

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