alexa Successful Radiofrequency Ablation of Medullary Thyroid Carcinoma Bone Metastasis | OMICS International| Abstract
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Journal of Cancer Science & Therapy
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  • Research Article   
  • J Cancer Sci Ther/Vol.11.8 241(2019),

Successful Radiofrequency Ablation of Medullary Thyroid Carcinoma Bone Metastasis

Ugo Albisinni1, Margherita Bartocci2*, Paolo Spinnato1, Giancarlo Facchini1, Vincenzo De Biasi3 and Giorgio Stecconi Ortolani4
1Department of Radiological Sciences, Rizzoli Hospital, Bologna, Italy
2Department of Radiological Sciences, AUSL of Umbria 1, Perugia, Italy
3Division of Nuclear Medicine, ASMN of Reggio Emilia, Italy
4Division of Endocrinology, AUSL of Parma, Italy
*Corresponding Author : Margherita Bartocci, Department of Radiological Sciences, AUSL of Umbria 1, Perugia, Italy, Tel: +393204062543, Email: [email protected]

Received Date: Jul 19, 2019 / Accepted Date: Aug 08, 2019 / Published Date: Aug 16, 2019


Purpose: Medullary thyroid carcinoma is a rare cancer that arises from parafollicular or C cells which secrete calcitonin. The prognosis is usually poor because, at the time of diagnosis, either lymph node involvement or distant metastases are frequently present and there is no effective treatment for metastatic disease. We report our experience of the first case of solitary bone metastasis of medullary thyroid carcinoma treated with radiofrequency ablation.

Materials and methods: In September 2014 a patient with bone metastasis of medullary thyroid carcinoma was treated with computer tomography guided radiofrequency ablation. The patient was then followed by periodical physical examinations, serum calcitonin levels and Gallium-68 somatostatin receptor positron emission tomography - computed tomography (68Ga PET-CT) until December 2018.

Results: Neither acute nor long-term complications were observed. Local recurrence at the site of the ablated metastasis was not encountered during follow-up, in particular, the patient obtained a partial response using biochemical parameters and a complete response using metabolic parameters.

Conclusion: Radiofrequency ablation could be a new useful treatment modality in bone metastasis of medullary thyroid carcinoma, but further studies are necessary to determine the precise role that this therapy should play in the management of this pathological condition.

Keywords: Radiofrequency ablation; Medullary thyroid carcinoma; Bone metastasis; Biochemical parameters

Citation: Albisinni U, Bartocci M, Spinnato P, Facchini G, Biasi VD, et al. (2019) Successful Radiofrequency Ablation of Medullary Thyroid Carcinoma Bone Metastasis. J Cancer Sci Ther 11: 241-243.

Copyright: © 2019 Albisinni U, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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