Sudden Unexpected Death in ParkinsonÃ¢ÂÂs Disease and the Pharmacological Modulation of the Ca2+/cAMP Signaling Interaction: A Shot of Good News
- *Corresponding Author:
- Leandro Bueno Bergantin
Laboratory of Autonomic and Cardiovascular Pharmacology
Department of Pharmacology, Escola Paulista de Medicina
Universidade Federal de São Paulo (UNIFESP), Rua Pedro de Toledo
669-Vila Clementino, São Paulo-SP, Brazil
E-mail: [email protected]
Received Date: April 07, 2017; Accepted Date: April 18, 2017; Published Date: April 25, 2017
Citation: Caricati-Neto A, Scorza FA, Scorza CA, Cysneiros RM, Menezes- Rodrigues FS, et al. (2017) Sudden Unexpected Death in Parkinson’s Disease and the Pharmacological Modulation of the Ca2+/cAMP Signaling Interaction: A Shot of Good News. Brain Disord Ther 6: 231. doi: 10.4172/2168-975X.1000231
Copyright: © 2017 Caricati-Neto A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This discusses how pharmacological modulation of the Ca2+/cAMP signaling interaction could be an important neuroprotective and cardioprotective strategy to protect the dopaminergic neurons from cell death related to Parkinson’s disease (PD) and at the same time to prevent the cardiac collapse in sudden unexpected death in PD.