alexa Surgical Resection of a Small Cell Carcinoma Primary Tumor of the Parotid Gland with Perineural and Skull Base Involvement | OMICS International
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

Surgical Resection of a Small Cell Carcinoma Primary Tumor of the Parotid Gland with Perineural and Skull Base Involvement

Zimmerman Z1, Lehman J1, Hoffman-Ruddy B1,2 , Silverman E3*, and Baekey PA4
1Ear, Nose, Throat and Plastic Surgery Associates, Orlando, FL, USA 32806
2University of Central Florida, Orlando, FL, USA 32816
3University of Florida, Gainesville, FL, USA 32610
4Central Florida Pathologists,Orlando, FL, USA 32803
Corresponding Author : Erin P Silverman
Department of Physiology
University of Florida, USA PO Box 100144
Gainesville, FL 32610, USA
Tel: 352-339-4100
E-mail: [email protected]
Received October 22, 2014; Accepted February 20, 2015; Published February 24, 2015
Citation: Zimmerman Z, Lehman J, Hoffman-Ruddy Bari, Silverman EP, Baekey PA, et al. (2015) Surgical Resection of a Small Cell Carcinoma Primary Tumor of the Parotid Gland with Perineural and Skull Base Involvement. J Clin Case Rep 5: 494. doi:10.4172/2165-7920.1000494
Copyright: ©2015 Zimmerman Z, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: One of the rarest tumors of the parotid gland is a Small Cell Carcinoma (SmCC) of neuroendocrine or ductal origin. These lesions tend to be aggressive, often invading bone and nerve and carry a grave prognosis for the patient. Presently there is no standardized treatment protocol and no consensus to tumor management. Case Report: This case report is of a 70 year-old male with a right-sided facial mass, facial pain, severe otalgia, weight loss, and right-sided facial paralysis. Subsequent imaging and Fine Needle Aspiration (FNA) revealed T4aN2bM0 SmCC of the parotid gland with facial nerve enhancement and skull base erosion. The patient underwent major extirpative surgery including radical neck dissection, total parotidectomy with facial nerve resection and cable graft, and partial temporal bone resection as the initial step in a combined modality therapy The patient has done very well post-operatively. Conclusion: This case report describes the successful, aggressive surgical management of locally and regionally advanced SmCC of the parotid gland. Although the prognosis for patients with SmCC of the parotid gland is typically grave, the absence of distant metastatic disease in the presented case provided the rationale for an aggressive surgical approach with a curative, rather than palliative, focus.

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