alexa Synthesis, Characterization and Biological Applications of Transition Metal Complexes of [no] Donor Schiff Bases
ISSN: 0974-276X

Journal of Proteomics & Bioinformatics
Open Access

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Research Article

Synthesis, Characterization and Biological Applications of Transition Metal Complexes of [no] Donor Schiff Bases

Khurram Shoaib1, Wajid Rehman1*, Bakhtiar Mohammad1* and Saqib Ali2

1Department of Chemistry, Hazara University, Mansehra, Pakistan

2Department of Chemistry, Quaid-i-Azam University, 45320, Islamabad, Pakistan

*Corresponding Author:
Wajid Rehman
Department of Chemistry
Hazara University, Mansehra, Pakistan
E-mail: [email protected]

Bakhtiar Mohammad
Department of Chemistry
Hazara University
Mansehra, Pakistan
E-mail: [email protected]

Received Date: November 12, 2011; Accepted Date: December 17, 2011; Published Date: January 30, 2012

Citation: Shoaib K, Rehman W, Mohammad B, Ali S (2012) Synthesis, Characterization and Biological Applications of Transition Metal Complexes of [no] Donor Schiff Bases. J Proteomics Bioinform 6: 153-157. doi: 10.4172/jpb.1000274

Copyright: © 2012 Shoaib K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Ten novel transition metal complexes of N,O donor ligands have been synthesized by the reaction of ligands with metal acetates in 2:1 molar ratio. These reactions were carried out under reflux in methanol for 3-6 hours. The ligands and their transition metal complexes were characterized on the basis of physical properties, elemental analysis, Infrared spectroscopy, Magnetic susceptibility, Ultraviolet and Atomic absorption spectroscopy and 1H-13C NMR spectroscopy. The FT- IR spectra of the complexes indicated that ligands behaved in bidentate manner coordinating via the nitrogen and oxygen. 1H-NMR and 13C-NMR data of the ligands in pure and complex form confirmed the formation of the complexes. Other analytical techniques demonstrated that transition metal complexes of Cu, Ni, Co and Zn are four coordinated and those of Mn are six coordinated. Furthermore, antibacterial activities have been discussed.


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