alexa Synthesis of 14-aryl/alkyl -14H-dibenzo [a,j] Xanthenes and Nitriles Catalyzed by KHSO4-SiO2 Under Ultra-sonication and Solvent-free Conditions
ISSN: 2157-7609

Journal of Drug Metabolism & Toxicology
Open Access

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Research Article

Synthesis of 14-aryl/alkyl -14H-dibenzo [a,j] Xanthenes and Nitriles Catalyzed by KHSO4-SiO2 Under Ultra-sonication and Solvent-free Conditions

Reddi Mohan Naidu Kalla1*, Muralikrishna Akkarapalli2 and Hasnah Osman2

1Department of Chemistry, Yogananda Inistitute of Technology and Science, Tirupati, India

2School of Chemical Science, University of Sains Malaysia, Malaysia

*Corresponding Author:
Reddi Mohan Naidu Kalla
Department of Chemistry
Yogananda Inistitute of Technology and Science
Tirupati 517520, India
E-mail: [email protected]

Received Date: June 06, 2014; Accepted Date: June 30, 2014; Published Date: July 08, 2014

Citation: Kalla RMN, Akkarapalli M, Osman H (2014) Synthesis of 14-aryl/ alkyl-14H-dibenzo [a,j] Xanthenes and Nitriles Catalyzed by KHSO4-SiO2 Under Ultra-sonication and Solvent-free Conditions. J Drug Metab Toxicol 5:167. doi: 10.4172/2157-7609.1000167

Copyright: © 2014 Kalla RMN, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

14-Aryl/Alkyl-14H-dibenzo[a,j]Xanthenes and Nitriles were synthesized by a green, simple and highly efficient one pot synthetic method. The dehydration of 2-napthol with aldehyde leads to xanthenes and aldoximes to nitriles catalysed by KHSO4-SiO2 in neat and ultrasonication to afford the title compounds in high yields and relatively short reaction times.

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