alexa Systemic Buffers in Cancer Therapy: The Example of Sodium Bicarbonate; Stupid Idea or Wise Remedy?
ISSN: 2161-0444

Medicinal Chemistry
Open Access

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Review Article

Systemic Buffers in Cancer Therapy: The Example of Sodium Bicarbonate; Stupid Idea or Wise Remedy?

Seraina Faes and Olivier Dormond*

Department of Visceral Surgery, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Pavillon 4, Av. de Beaumont, 1011 Lausanne, Switzerland

*Corresponding Author:
Olivier Dormond
Department of Visceral Surgery
Centre Hospitalier Universitaire Vaudois and University of Lausanne
Pavillon 4, Av. de Beaumont, 1011 Lausanne, Switzerland
Tel: +41795560340
Fax: +41213140824
E-mail: olivier.dormond@chuv.ch

Received date: December 04, 2015; Accepted date: December 28, 2015; Published date: December 30, 2015

Citation: Faes S, Dormond O (2015) Systemic Buffers in Cancer Therapy: The Example of Sodium Bicarbonate; Stupid Idea or Wise Remedy?. Med chem 5:540-544. doi:10.4172/2161-0444.1000314

Copyright: © 2015 Faes S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Despite recent therapeutic progress, cancer remains a major cause of death in industrialized countries. As a consequence, alternative treatments attract the attention of a growing number of patients. Among these therapies, the use of sodium bicarbonate to fight cancer has gained considerable interest. According to self-medication reports available on the internet, sodium bicarbonate is viewed by many patients as a simple, costless and efficient anti-cancer agent. Although no clinical study has demonstrated an anti-cancer activity of sodium bicarbonate up to date, emerging experimental reports indicate, that sodium bicarbonate may slow the progression of cancer. Here, we highlight the rationale to use sodium bicarbonate in cancer therapy and further enumerate experimental evidence for its anti-tumoral activity. Finally, we speculate about a future role of sodium bicarbonate in cancer therapy.

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