alexa Systemic Inflammatory Response and Fat Necrosis of Perineal Soft Tissues: A Rare Complication of Bladder-Drained Transplanted Pancreas Leak | OMICS International
ISSN: 2165-7092

Pancreatic Disorders & Therapy
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Review Article

Systemic Inflammatory Response and Fat Necrosis of Perineal Soft Tissues: A Rare Complication of Bladder-Drained Transplanted Pancreas Leak

Sara A. Mansfield1*, William J. Melvin2, Brent Carlyle3, Steven Sun1, Justin T. Huntington1, David C. Evans1 and Amy Rushing1
1Department of General Surgery, The Ohio State University, USA
2Department of Medicines, The Ohio State University, College of Medicine, Columbus, USA
3Department of Urology, The Ohio State University, Columbus, USA
Corresponding Author : Sara A. Mansfield
Department of General Surgery, The Ohio State University
395 W 12th Avenue, Columbus, OH, 43210, USA
Tel: 7405917260
E-mail: [email protected]
Received: November 23, 2015; Accepted: February 19, 2016; Published: February 24, 2016
Citation: Mansfield SA, Melvin WJ, Carlyle B, Sun S, Huntington JT, et al. (2016) Systemic Inflammatory Response and Fat Necrosis of Perineal Soft Tissues: A Rare Complication of Bladder-Drained Transplanted Pancreas Leak. Pancreat Disord Ther 6:169. doi:10.4172/2165-7092.1000169
Copyright: © 2016 Mansfield SA et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Pancreatic transplant is increasingly being performed for management of diabetes. There are known complications, specifically related to exocrine drainage of the pancreas, with enteric versus bladder drainage being options. Here we present a unique complication of leakage of the pancreaticocystostomy, likely secondary to severe urethritis and obliteration of the urethra. Accumulation of pancreatic enzymes in the subcutaneous tissues led to fat necrosis of the scrotum and groin with severe systemic inflammatory response syndrome. Presentation mimicked an infectious soft tissue infection that failed antibiotic management. This highlights a unique clinical entity mimicking infection. This patient required debridement, urinary diversion, and a multidisciplinary approach to treatment.

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