alexa Targeting Immune-Evasion Mechanisms as a Possible New Approach in the Fight against Tuberculosis

Immunological Disorders & Immunotherapy
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Review Article

Targeting Immune-Evasion Mechanisms as a Possible New Approach in the Fight against Tuberculosis

Roberto Nisini*

Department of Infectious, Parasitic and Immune-Mediated Diseases, National Institute of Health, Viale Regina Elena 299, 00161 Rome, Italy

*Corresponding Author:
Roberto Nisini
Department of Infectious
Parasitic and Immune-Mediated
National Institute of Health
Viale Regina Elena 29900161 Rome, Italy
Tel: +390649902659
E-mail: [email protected]

Received date: October 06, 2015; Accepted date: November 06, 2015; Published date: November 12, 2015

Citation: Nisini R (2015) Targeting Immune-Evasion Mechanisms as a Possible New Approach in the Fight against Tuberculosis. Immunol Disord Immunother 1:101.

Copyright: © 2015 Nisini R. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The emergence of multidrug resistant Mycobacterium tuberculosis (Mtb) strains, the difficulties in the development of new safe therapies or the production of a protective vaccine against tuberculosis make the study of the strategies developed by Mtb to escape from the host immune system an important source of potential targets of immunointervention in the fight against tuberculosis. A mechanism of immune-evasion specific for the post-primary tuberculosis based on the differentiation of disabled antigen presenting cells is described.

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