alexa Taste Receptor Tas2r5 and Tas1r3 is Expressed in Sublingual Gland | OMICS International| Abstract
ISSN: 2161-0444

Medicinal Chemistry
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Research Article   
  • Med chem (Los Angeles) 2018, Vol 8(5): 127
  • DOI: 10.4172/2161-0444.1000504

Taste Receptor Tas2r5 and Tas1r3 is Expressed in Sublingual Gland

Feng Li*, Bowen Niu and Mengmin Zhu
Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China
*Corresponding Author : Feng Li, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China, Tel: 8613651824980, Email: [email protected]

Received Date: May 14, 2018 / Accepted Date: May 21, 2018 / Published Date: May 26, 2018

Abstract

Type 2 taste receptors (TAS2Rs), a large family of GPCRs, were first discovered in the gustatory system, and are co-expressed in a subset of taste receptor cells and detect bitter-tasting compounds. Type 1 taste receptors (TAS1R3) function as an obligate partner for both the umami receptor and the sweet receptor. Recently, it has become clear that taste receptors are also expressed outside the gustatory system. Here, with Tas2r5-Cre/GFP and Tas1r3-Cre/GFP transgenic mice, the expression of taste receptors (Tas1r3 or Tas2r5) is observed in serous gland and mucous gland of tongue. Taste signal transduction cascade (Gnat3 and PLC-β2) is also detected in serous gland and mucous gland of tongue. After DTA expression in Tas2r5+ and Tas1r3+ cells, the expression of taste receptors and taste signal transduction cascade is ablated in serous and mucous gland of tongue.

Keywords: Serous gland; Mucous gland; Taste receptor; Tongue; Transgenic mice

Citation: Li F, Niu B, Zhu M (2018) Taste Receptor Tas2r5 and Tas1r3 is Expressed in Sublingual Gland. Med Chem (Los Angeles) 8: 127-135. Doi: 10.4172/2161-0444.1000504

Copyright: © 2018 Li F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Select your language of interest to view the total content in your interested language

Post Your Comment Citation
Share This Article
Recommended Conferences
Recommended Conferences
Viewmore
Article Usage
  • Total views: 1744
  • [From(publication date): 0-2018 - Jan 21, 2020]
  • Breakdown by view type
  • HTML page views: 1664
  • PDF downloads: 80
Top