alexa Temperature Effects on the Basic Reproductive Number (R0) Of West Nile Virus, Based On Ecological Parameters: Endemic Vs. New Emergence Regions
ISSN: 2329-891X

Journal of Tropical Diseases & Public Health
Open Access

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Research Article

Temperature Effects on the Basic Reproductive Number (R0) Of West Nile Virus, Based On Ecological Parameters: Endemic Vs. New Emergence Regions

Ariel Kushmaro1, Tamara Awerbuch-Friedlander2*and Richard Levins2

1Department of Biotechnology Engineering, Faculty of Engineering Sciences, Ben Gurion University, Beer Sheba 84105, Israel

2Department of Population and International Health Harvard School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, USA

*Corresponding Author:
Tamara Awerbuch-Friedlander
Department of Global Health and Population
Harvard School of Public Health
665 Huntington Ave, Boston, MA 02115, USA
Tel: 617- 432 – 2505
E-mail: [email protected]

Received Date: October 21, 2015 Accepted Date: November 13, 2015 Published Date: November 20, 2015

Citation: Kushmaro A, Friedlander TA, Levins R (2015) Temperature Effects on the Basic Reproductive Number (R0) Of West Nile Virus, Based On Ecological Parameters: Endemic Vs. New Emergence Regions. J Trop Dis: S1-001. doi:10.4172/2329-891X.1000S1-001

Copyright: © 2015 Kushmaro A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



This study is to compare the Basic Reproduction Number of West Nile Virus in new-emergence regions to that of endemic ones, given that there is global warming and that R0 is a function of temperature sensitive parameters. It has been suggested that elevated temperatures via global warming affect the spread of vector-borne diseases. West Nile virus (WNV), an arbovirus, is transmitted to hosts mainly by mosquitoes of the genera Culex, and amplified through an enzootic cycle where mostly birds are the reservoir. Parameters involved in the amplification are temperature sensitive, thus we compare endemic to new-emergence regions for their susceptibility to West Nile Virus (WNV) based on their basic reproductive number (R0) which is a complex function of temperature dependent parameters. R0 for West Nile Virus indicates that new emergence regions are more vulnerable to outbreaks than endemic regions; that once introduced WNV will spread there more rapidly even in lower temperatures. The analysis suggests that the high susceptibility of birds in new emergence areas along with temperature sensitive parameters related to the vector, may explain in a complex manner, the higher WNV propagation in these regions, as it is happening in North and Central America.

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