Journal of Coastal Zone Management

Abstract

The Acute Toxicity and Bone-Marrow Micronucleus Tests of Water Extract from Avicennia Marina Fruits in Mice

Gao Xiu-mei Han Wei-Dong Yu Zen-ji

The acute toxicity and mutagenesis of water extract from Avicennia marina fruits in mice were studied
with the oral acute toxicity test according to Karber’s method and the bone-marrow micronucleus test
for mutagenic observation.The results showed the water extract from A. marina fruits presented theacute
per oral toxicity at LD50 >10.000 mg/kg; the bone-marrow nicrobucleus test indicated no mutagenic
effects. Water extract from A.Marina fruits belong to non toxic compounds and has no mutagenic effects
under the experimental conditions.