alexa The Application of Metagenomic Approaches in the Manage
ISSN: 2329-9088

Tropical Medicine & Surgery
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Review Article

The Application of Metagenomic Approaches in the Management of Infectious Diseases

Jinhua Wu1, Kaiye Cai1 and Qiang Feng1,2*

1Beijing Genomics Institute- Shenzhen Main Building, Beishan Industrial Zone, Yantian District, Shenzhen, China

2Shenzhen Engineering Laboratory of Detection and Intervention of Human Intestinal Microbiome, Shenzhen, China

*Corresponding Author:
Qiang Feng
Beijing Genomics Institute-Shenzhen Main Building
Beishan Industrial Zone, Yantian District
Shenzhen, 518083, China
Tel: +86-755-25273620
Fax: +86-755-25273620
E-mail: [email protected]

Received Date: July 04, 2015 Accepted Date: September 01, 2015 Published Date: September 04, 2015

Citation: Wu J, Cai K, Feng Q (2015) The Application of Metagenomic Approaches in the Management of Infectious Diseases. Trop Med Surg 3:196. doi:10.4172/2329-9088.1000196

Copyright: © 2015 Wu J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Over the past decades, although billions of dollars has been invested and much progress has been made in the prevention and surveillance of infectious diseases, the mortality caused by these diseases is still hovering at high level. Infectious diseases are constantly threatening lives of millions of people around the world. For the diagnosis of these diseases, traditional culture-dependent methods are playing vital roles in clinical practice, but they still cannot meet the requirement of rapid detection of both known and unknown pathogens in a high-throughput mode. The emergence of next-generation sequencing (NGS) technology has greatly promoted the development of genome research, and the NGS-based metagenomics is gaining more and more attention as a potential technique for the management of infectious diseases. This review gives a brief summarization of the application of metagenomics in infectious diseases in recent years.

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