The Application of Stem Cell Based Tissue Engineering in Spinal Cord Injury Repair.Wanting Niu1,2 and Xiang Zeng3*
- Corresponding Author:
- Xiang Zeng
Department of Neurosurgery, Brigham and Women’s Hospital
Harvard Medical School, Boston, MA 02132, USA
E-mail: [email protected]
Received date:: October 14, 2015; Accepted date:: November 16, 2015; Published date:: November 24, 2015
Citation: Niu W, Zeng X (2015) The Application of Stem Cell Based Tissue Engineering in Spinal Cord Injury Repair. J Tissue Sci Eng 6:158. doi:10.4172/2157-7552.1000158
Copyright: © 2015 Niu W, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Spinal Cord Injury (SCI) results in the permanent functional impairment, leading to monoplegia, paraplegia or tetraplegia with tremendous social and economic burden. The intrinsic repair mechanism has been proven to be insufficient. The complex pathophysiology after injury imposes enormous challenging to functional recovery, given the most advanced medical intervention nowadays. Therefore, the development of effective therapeutic strategy for spinal cord injury management is in great need. Here we review a stem cell based tissue engineering approach under preclinical or clinical development for spinal cord injury, with a focus on promoting functional recovery after SCI, aiming to provide some beneficial suggestion on stem cell based tissue engineering design.