alexa The Benefit of Nutraceutical Food Supplementation and Antioxidants for the Treatment of the Infertile Couple and in Assisted Reproduction
ISSN: 2161-038X

Reproductive System & Sexual Disorders: Current Research
Open Access

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Special Issue Article

The Benefit of Nutraceutical Food Supplementation and Antioxidants for the Treatment of the Infertile Couple and in Assisted Reproduction

Frank H Comhaire1* and Wim Decleer2

1Professor emeritus, Ghent University, Brakelmeersstraat, 18, B 9830 Sint Martens-Latem, Belgium

2Director of Fertility-Belgium Clinic, Weststraat, 16-18, B 9880 Aalter, Belgium

Corresponding Author:
Frank H Comhaire
Professor emeritus, Ghent University
18, B 9830 Sint Martens-Latem, Belgium
E-mail: [email protected]

Received Date: November 21, 2011; Accepted Date: March 20, 2012; Published Date: March 24, 2012

Citation: Comhaire FH, Decleer W (2012) The Benefit of Nutraceutical Food Supplementation and Antioxidants for the Treatment of the Infertile Couple and in Assisted Reproduction. Reproductive Sys Sexual Disord S1:004. doi:10.4172/2161-038X.S1-004

Copyright: © 2012 Comhaire FH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Varicocele, male accessory gland infection, immunological infertility, and idiopathic oligozoospermia are the main causes of male infertility. Disturbances of ovulation, pelvic inflammatory disease, and endometriosis are common causes of female reproductive failure. The mechanisms by which these causes interfere with male and female reproduction are inflammation through prostaglandins and cytokines, and oxidative overload damaging the cell membrane, inducing mutagenesis of the DNA, and impairing mitochondrial energy production. A unique nutraceutical food supplement (NFS) has been created that aims at correcting these mechanisms and at reducing the influence of detrimental environmental factors. The efficiency of adding this NFS to causal therapy, or in assisted reproduction is expressed as numbers of couples needed to treat (NNT) to obtain one additional pregnancy. When the NFS is added to the treatment of varicocele the NNT is 3. Treating both partners with the NFS resulted in one additional ongoing pregnancy for every 4 IVF treatments.

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