alexa The Biological Performance of Crataegus songarica Against Certain Infectious Fungal and Bacterial Diseases
ISSN: 0974-8369

Biology and Medicine
Open Access

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Research Article

The Biological Performance of Crataegus songarica Against Certain Infectious Fungal and Bacterial Diseases

Shafiq Ahmad Tariq1*, Muhammad Nisar2, Haroon Khan3* and Muhammad Raza Shah4

1Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan

2Institute of Chemical Sciences, University of Peshawar, 25120, Peshawar, Pakistan

3Department of Pharmacy, Abdul Wali Khan University Mardan, Pakistan

4HEJ Research Institute, International Center for Chemical and Biological Sciences, Karachi University, Karachi, Pakistan

*Corresponding Author:
Dr. Haroon Khan
Principal, Gandhara College of Pharmacy
Gandhara University, Peshawar, Pakistan
E-mail: [email protected]

Received Date: October 05, 2013; Accepted Date: October 21, 2013; Published Date: October 28 2013

Citation: Tariq SA, Nisar M, Khan H, Shah MR (2014) The Biological Performance of Crataegus songarica Against Certain Infectious Fungal and Bacterial Diseases. Biol Med 6:194. doi: 10.4172/0974-8369.1000194

Copyright: © 2014 Tariq SA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 
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Abstract

The goal of the present study was to evaluate the antibacterial and antifungal of the crude extract/fractions of Crataegus songarica against six bacterial and fungal strains. The extract/fractions demonstrated significant susceptibility against tested bacteria namely Escherchia coli, Bacillus subtilis and Shigella flexeneri illustrated the most susceptibility were with MICs 150 µg/mL, 390 µg/mL and 220 µg/mL respectively. Meanwhile Antifungal activity was also recorded table and the crude extract and fractions showed marked activity against Trichophyton longifusus, Aspergillus flavus, Microspoum canis and Fusarium solani with MICs 220 µg/mL, 180 µg/mL, 110 µg/mL and 160 µg/mL respectively. Based on the obtained results, C. songarica could be considered a new natural healing agent for the treatment of various infectious diseases.

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