alexa The CRISPR-Cas9 System: A New Dawn in Gene Editing | OMICS International | Abstract
ISSN: 1948-593X

Journal of Bioanalysis & Biomedicine
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Review Article

The CRISPR-Cas9 System: A New Dawn in Gene Editing

Nurul Husna Shafie*, Mohamed Saleem, Emmanuel Jairaj Moses, Siti Razila Abdul Razak, and Narazah Mohd Yusoff*

Advanced Medical and Dental Institute (AMDI), Universiti Sains Malaysia, Bandar Putra Bertam, 13200 Kepala Batas, Penang, Malaysia

*Corresponding Author:
Nurul Husna Shafie
Advanced Medical and Dental Institute (AMDI)
Universiti Sains Malaysia, Bandar Putra Bertam
13200 Kepala Batas, Penang, Malaysia
E-mail: [email protected]

Narazah Mohd Yusoff
Advanced Medical and Dental Institute (AMDI)
Universiti Sains Malaysia, Bandar Putra Bertam
13200 Kepala Batas, Penang, Malaysia
E-mail: [email protected]

Received Date: September 12, 2014; Accepted Date: November 03, 2014; Published Date: November 07, 2014

Citation: Shafie NH, Saleem M, Moses EJ, Razak SRA, Yusoff NM (2014) The CRISPR-Cas9 System: A New Dawn in Gene Editing. J Bioanal Biomed 06: 045-048. doi: 10.4172/1948-593X.1000109

Copyright: © 2014 Shafie NH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats with CRISPR-associated protein 9) system is a genome editing system that is easy to design, highly specific, efficient, robust, and well suited for highthroughput and multiplexed gene editing for a variety of cell types and organisms. In this review we describe current applications of this new system, which is growing in popularity and is increasingly being employed to selectively control gene expression on a genome-wide scale.

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