alexa The Current Practice of Hypertensive Crises Treatment a
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

The Current Practice of Hypertensive Crises Treatment and the Underestimated Role of Clinical Pharmacists in Ambo Hospital Medical Ward, Ethiopia

Minyahil A Woldu1*#, Jimma L Lenjisa2#, Gobezie T Tegegne2, Derartu G Yadeta2 and Deressa T Chala2
1Department of Pharmacology and Clinical Pharmacy, School of pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
2Ambo University, College of Medicine and Health Sciences, Department of Pharmacy, Clinical Pharmacy Unit; Ambo, Ethiopia
#These authors have contributed equally to the paper
Corresponding Author : Minyahil A Woldu
Department of Pharmacology
and Clinical Pharmacy
School of Pharmacy
College of Health Sciences
Addis Ababa University
Addis Ababa-Ethiopia
Tel: +251912648527
E-mail: [email protected]
Received August 22, 2014; Accepted October 22, 2014; Published October 24, 2014
Citation: Woldu MA, Lenjisa JL, Tegegne GT, Yadeta DG, Chala DT (2014) The Current Practice of Hypertensive Crises Treatment and the Underestimated Role of Clinical Pharmacists in Ambo Hospital Medical Ward, Ethiopia. J Clin Case Rep 4:445. doi:10.4172/2165-7920.1000445
Copyright: © 2014 Woldu MA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Background: Hypertension is an extremely common clinical problem, affecting approximately 1 billion individuals worldwide. An estimated 1% to 2% of patients with chronic hypertension will at some time develop hypertensive crises (Hypertensive urgency and emergency). Hypertensive urgency and emergency are differentiated by the absence or presence of acute end-organ damage, respectively. The blood pressure of patients with hypertensive emergencies should be reduced rapidly during the treatment. It should not be reduced to the normal value, but by approximately 20-30% of the baseline value. The reason for a stepwise reduction in blood pressure is the fact that patients with chronic hypertension have an altered auto regulation curve.


Case presentation: A 60 year old male patient, who has been a known hypertensive patient admitted due to sudden onset of body weakness, difficulty of speech, diverted lips towards the left side, difficulties in eating, moving, coughing and inability to move right side of his extremities since one day. On P/E the pt. was severely sick looking, and unconscious.

Conclusion: A number of both parenteral and oral antihypertensive drugs can be used in these patients. Treatment of hypertensive crises in patients with hypertensive encephalopathy, intracranial haemorrhage, subarachnoid haemorrhage, and thrombotic stroke has been recommended to be initiated with nicardipine, fenoldopam, nimodipine, flunarizine or labetalol.

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