alexa The Dynamic Measurement of Procalcitonin in Neonatal Pu
ISSN: 2155-9562

Journal of Neurology & Neurophysiology
Open Access

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Research Article

The Dynamic Measurement of Procalcitonin in Neonatal Purulent Meningitis

Bing Zhang1, Peng Chen2, Mengping Shen1, Qunxing Ding3and Haiyan Zhu3*

1Department of Neonatology, First People’s Hospital, Zheng Zhou, He Nan, P. R. China

2Department of Clinic Laboratory, First People’s Hospital, Zheng Zhou, He Nan, P. R. China

3Department of Biological Sciences, Kent State University at East Liverpool, East Liverpool, OH, USA

Corresponding Author:
Haiyan Zhu
Assistant professor
Kent State University
Biological sciences 400 E 4th St
East Liverpool, Ohio 43920, USA
Tel: 330-382-7573
E-mail: [email protected]

Received date: July 16, 2014; Accepted dat: August 12, 2014; Published date:August 18, 2014

Citation: Zhang B, Chen P, Shen M, Ding X, Zhu H (2014) The Dynamic Measurement of Procalcitonin in Neonatal Purulent Meningitis . J Neurol Neurophysiol 5:221. doi:10.4172/2155-9562-5-1000221

Copyright: © 2014 Zhang B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Neonatal purulent meningitis is a significant cause of neonatal disability and death. The early diagnosis and
effective treatment are critical for neonatal purulent meningitis. Procalcitonin (PCT) is currently used as a clinical
diagnosis marker of inflammation and infection, such as sepsis. Due to the lower immunity of neonates and the
atypical symptoms of neonatal purulent meningitis, it is challenging to obtain reliable information of the development,
diagnosis, treatment and prognosis of neonatal purulent meningitis. This study monitored the dynamic change of the
PCT levels in 48 neonatal patients after the standard treatment and found out that the PCT level may not be a
distinguish diagnosis marker but a useful indicator for efficacy of the treatment and prognosis specifically in neonatal
purulent meningitis.


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