alexa The Effect of Piezoelectric Stimulation in Patients with Low Fertilization Potential | OMICS International | Abstract
ISSN: 2161-0436

Human Genetics & Embryology
Open Access

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Research Article

The Effect of Piezoelectric Stimulation in Patients with Low Fertilization Potential

Volkan Baltaci1*, Yasemin Aktas2, Evrim Unsal2, Ozge Uner Ayvaz2, Feriba Turhan Eryilmaz2, Bilge Sinano?lu Ekin2, Sertaç Şen2,Aysun Baltacı2

1 Faculty of Medicine, Department of Medical Genetics, Ufuk University, Ankara, Turkey

2 Gen Art Woman Health and Reproductive Biotechnology Center, Ankara, Turkey

*Corresponding Author:
Volkan Baltaci
Faculty of Medicine
Department of Medical Genetics
Ufuk University, Ankara, Turkey
Tel: +903125867400
E-mail: [email protected]

Received February 16, 2014; Accepted April 21, 2014; Published April 24, 2014

Citation: Baltaci V, Aktas Y, Unsal E, Ayvaz OU, Eryilmaz FT, et al. (2014) The Effect of Piezoelectric Stimulation in Patients with Low Fertilization Potential. Human Genet Embryol 4:122. doi: 10.4172/2161-0436.1000122

Copyright: © 2014 Baltaci V, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Objective:
To assess the value of the electrical activation of oocytes in ICSI patients with previous limited fertilization outcomes.
Design:
Prospective randomized study.
Settings:
Clinical IVF laboratory.
Patient(s):
A hundred and seven couples undergoing ICSI with possible low fertilization outcomes.
Intervention(s):
TESE, TESA, ICSI with Piezoelectric Activation
Main Outcome Measure(s):
Fertilization, clinical pregnancy rates, embryo grades.
Result(s):
Patients were subdivided into six study groups. In Group I, testicular elongated spermatids were used and 27.9% fertilization, 2.3% clinical pregnancy rates were evaluated. In testicular immotile spermatozoa injected group (Group II), 56.5% fertilization and 50% clinical pregnancy rates were obtained. 66.7% fertilization and 30%clinical pregnancy rates were achieved in Group III with testicular motile spermatozoa. In Group IV, patients with severe oligozoospermia, 64% fertilization and 28.6% clinical pregnancy rates were achieved. Group V included patients with total immotile spermatozoa and fertilization and clinical pregnancy rates were 50% and 57.1% respectively. In patients with history of low fertilization rate (Group VI), 38.7% fertilization and 19% clinical pregnancy rates were obtained.
Conclusion(s):
Piezoelectric stimulation can be used for patients with low fertilization rates and total immotile spermatozoa; as we detected an improvement in the fertilization and clinical pregnancy rates of these patients.

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