alexa The Ethical Use of Placebo in Pediatric Research | OMICS International | Abstract
ISSN: 2155-9627

Journal of Clinical Research & Bioethics
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Review Article

The Ethical Use of Placebo in Pediatric Research

Rita A. Gómez-Díaz1*, Niels Wacher1, Susana Castañón1, Carlos A. Aguilar-Salinas2, Susan Drier-Jonas1 and Alberto Lifshitz-G?inzberg3

1Unidad de Investigación Médica en Epidemiología Clínica, UMAE Hospital de Especialidades Mexico

2Departmento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Mexico

3Jefe de la Unidad de Educación, Investigación y Políticas de Salud, Dirección de Prestaciones Médicas Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico

*Corresponding Author:
Rita A. Gómez-Díaz
MD Av. Cuauhtémoc No. 330, Col
Doctores. México City 06720, Mexico
Tel: 52-55-5627 6900 Ext 21481
Fax: 52- 55-10541599
E-mail: [email protected]

Received Date: November 08, 2012; Accepted Date: December 17, 2012; Published Date: December 19, 2012

Citation: Gómez-Díaz RA, Wacher N, Castañon S, Aguilar-Salinas CA, Drier-Jonas S, et al. (2011) The Ethical Use of Placebo in Pediatric Research. J Clinic Res Bioeth 2:120 doi: 10.4172/2155-9627.1000120

Copyright: © 2011 Gómez-Díaz RA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The use of placebo remains one of the more hotly debated elements of this facet of medicine. Therefore, the objective of this document is to raise some reflections about its use in children. The World Medical Association, Nuremberg Proceedings, and, in many countries, local regulations consider the principles of non-malfeasance and justice, which consist in offering the best therapies available to children, as long as they are previously evaluated, regardless of race, economic level or social status. However, the special ethical dilemmas of children are not adequately addressed. This article suggests a list of considerations for the use of children in placebo-controlled trials, recommends ethical guidelines, and offers an algorithm based on that proposed for adults for evaluating the ethics of a placebo-controlled trial.

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