The Ethical Use of Placebo in Pediatric Research
- *Corresponding Author:
- Rita A. Gómez-Díaz
MD Av. Cuauhtémoc No. 330, Col
Doctores. México City 06720, Mexico
Tel: 52-55-5627 6900 Ext 21481
Fax: 52- 55-10541599
E-mail: [email protected]
Received Date: November 08, 2012; Accepted Date: December 17, 2012; Published Date: December 19, 2012
Citation: Gómez-Díaz RA, Wacher N, Castañon S, Aguilar-Salinas CA, Drier-Jonas S, et al. (2011) The Ethical Use of Placebo in Pediatric Research. J Clinic Res Bioeth 2:120 doi: 10.4172/2155-9627.1000120
Copyright: © 2011 Gómez-Díaz RA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The use of placebo remains one of the more hotly debated elements of this facet of medicine. Therefore, the objective of this document is to raise some reflections about its use in children. The World Medical Association, Nuremberg Proceedings, and, in many countries, local regulations consider the principles of non-malfeasance and justice, which consist in offering the best therapies available to children, as long as they are previously evaluated, regardless of race, economic level or social status. However, the special ethical dilemmas of children are not adequately addressed. This article suggests a list of considerations for the use of children in placebo-controlled trials, recommends ethical guidelines, and offers an algorithm based on that proposed for adults for evaluating the ethics of a placebo-controlled trial.