alexa The Growing Potential of Neurophysiology in Multiple Sclerosis
ISSN: 2376-0389

Journal of Multiple Sclerosis
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Letter to Editor

The Growing Potential of Neurophysiology in Multiple Sclerosis

Canham LJW1*, Western DG1,2, Walsh P3, Kane N3, Inglis K1and Cottrell DA1

1Bristol and Avon Multiple Sclerosis Service (BrAMS), Department of Neurosciences, Bristol Brain Centre, North Bristol NHS Trust, Southmead Hospital, Southmead Road, Westbury-On-Trym, Bristol BS10 5NB, UK

2Department of Mathematical Engineering, University of Bristol, UK

3The Grey-Walter Neurophysiology Department, North Bristol NHS Trust, Southmead Hospital, Southmead Road, Westbury-On-Trym, Bristol, BS10 5NB, UK

*Corresponding Author:
Canham LJW
Bristol and Avon Multiple Sclerosis Service (BrAMS)
Department of Neurosciences, Bristol Brain Centre
North Bristol NHS Trust, Southmead Hospital
Southmead Road, Westbury-On-Trym
Bristol BS10 5NB, UK
Tel: +441179505050
E-mail: [email protected]

Received date: August 25, 2016; Accepted date: November 21, 2016; Published date: November 28, 2016

Citation: Canham LJW, Western DG, Walsh P, Kane N, Inglis K, et al. (2016) The Growing Potential of Neurophysiology in Multiple Sclerosis. J Mult Scler (Foster City) 3:190. doi:10.4172/2376-0389.1000190

Copyright: © 2016 Canham LJW, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited



Neurophysiological techniques have a long history of clinical and research use in the setting of Multiple Sclerosis. With the output of evoked potential and electroencephalographic recordings being a direct consequence of the underlying functional integrity and activity of the nervous system it is unsurprising there is currently a resurgent interest in their possible use as biomarkers of disease related dysfunction. Herein we discuss the promise and possible pitfalls associated with their use in translational research of MS therapeutics. The numerous advantages of these methods are touched upon as demonstrated by their application to date. A number of obstacles which must be overcome prior to their successful widespread implementation are also outlined and readily achievable solutions discussed.


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